The increased activity of the LIMK1 isoform has been associated with several diseases including Alzheimer’s diseases (AD) (Heredia et al., 2006; Piccioli and Littleton 2014), cancer (Davila et al., 2007; Kang et al., 2021; Shi et al., 2021), and HIV (Vorster et al., 2011; Wen et al., 2014). The gene discussed is LIMK1; the disease is Alzheimer disease.