Figure 4(a) summarizes the infiltration of 22 types of immune cells in each sample.  Figure 4(b) shows the overall composition of immune cells in AD group and control group.  Figure 4(c) shows the co-expression correlation between 22 immune cell proportions. As shown in Figure 4(d), compared with normal control group, higher proportions of T cells CD4 memory activated, macrophages M2, and neutrophils could be detected in AD group, along with lower proportions of T cells follicular helper, T cells regulatory (Tregs), NK cells activated, and mast cells resting (P < 0.05). The gene discussed is CD4; the disease is Alzheimer disease.