Androgen biosynthesis and androgen receptor (AR)-mediated signaling pathway [7], PTEN (phosphatase and tensin homolog), a negative regulator of PI3K/AKT signaling pathway [8], and p53 (tumor suppressor protein 53) genes [9, 10], RAS signaling pathway [11] are differentially altered in PCa patients belonging to one racial/ethnic group compared to other groups. Here, PTEN is linked to posterior cortical atrophy.