The increase in COX2 and ACSL4 levels was greater in the AIH + AAV8-m-GPX4 group compared with the AIH + AAV8-EGFP group after GPX4 knockdown, while the relative protein expression of FTH1 was also significantly reduced (Figures 3(g) and 3(h); P < 0.05). The gene discussed is ACSL4; the disease is autoimmune hepatitis.