The univariate analysis showed that a higher HS was a significant predictor of AE in addition to BMI, IPF, mMRC (≥2), %FVC, percent predicted diffusing capacity of carbon monoxide (%DLco), KL-6 level, and percentage of neutrophils in BALF (Table 2). The gene discussed is MUC1; the disease is idiopathic interstitial pneumonia.