Among these pathways, the ‘PI3K-Akt signaling pathway,' ‘MicroRNAs in cancer,' ‘Proteoglycans in cancer,' ‘Cellular senescence,' ‘FoxO signaling pathway,' ‘Central carbon metabolism in cancer,' and ‘Cell cycle' are closely correlated with the carcinogenesis and development of BRCA. The gene discussed is AKT1; the disease is cancer.