Generally, the infiltration of macrophages, neutrophils, resting NK cells, and CAF was positively related to CEMIP expression with all or most algorithms in most carcinomas, including BC (Supplementary Figures S5, S6A and Figure 7A), while activated NK cells, CD8+ T cells, and CD4+ Th1 cells were opposite (Supplementary Figures S6, S7A) and other immune cell (that is., CD4+ T cells, B cells, and DC) infiltrations showed no clear unifying trends with these available algorithms (Supplementary Figures S7, S8). This evidence concerns the gene CD4 and breast cancer.