However, when we divided BC patients into ER+/PR+ and ER−/PR− groups, only OS of BC patients with ER+/PR+ was significantly negatively correlated with CEMIP expression, indicating that its prognostic prediction in BC patients with ER+/PR+ might be more significant since the patients with TNBC have been widely proved to have poor prognoses (Waks and Winer, 2019). This evidence concerns the gene ESR1 and breast cancer.