CEMIP and breast cancer: According to the univariate Cox regression analysis, we found that stage (HR = 2.2, p = 2.3e-07), age (HR = 1, p = 3.3e-06), node state (HR = 1.5, p = 0.00015), tumor states (HR = 1.5, p = 8e-04), metastasis status (HR = 4, p = 0.00045), and the expression level of CEMIP (HR = 1.1, p = 0.042) were significantly negative correlated to OS of BC patients as risk factors (Supplementary Table S2).