Porto et al. (2018a) compared the anti-infective potential of guavanin 2 as compared with its ancestors (Pg-AMP1 and fragment2), using the ‘abscess skin infection model’ with P. aeruginosa. All three AMPs in question presented activity against this bacterium, which can cause skin infections in healthy or immunocompromised patients (Pelegrini et al., 2008). This evidence concerns the gene JUP and skin infection.