There were significant differences between age (p<0.001 both in females and males), BMI (p<0.001 in females and males), GFR (p<0.001 in females and males), as well as serum FBG (p<0.001 in females and males), HbA1c (p=0.003 in females, p=0.017 in males), insulin (p=0.002 in females, p=0.002 in males), DM status (p<0.001 in females, p=0.026 in males), use of oral hypoglycemic agent use (p=0.002 in females, p<0.001 in males) and insulin resistance index (p<0.001 in females and males) of participants in different quartiles of CCC in both female and male groups (Table 1). The gene discussed is INS; the disease is diabetes mellitus.