In the Model 1, FLI was independently associated with serum FABP4 in the whole population (R2 = 0.127, standardized β = 0.323, P < 0.001), as well as in diabetic (R2 = 0.165, standardized β = 0.267, P < 0.001), obese (R2 = 0.149, standardized β = 0.303, P < 0.001) and metabolic syndrome (R2 = 0.170, standardized β = 0.259, P < 0.001) patients. The gene discussed is FABP4; the disease is metabolic syndrome.