On chromosomes 17 and 18, significant association was detected at previously described loci that regulate colon and lung cancer in the mouse, i.e., the QTLs Susceptibility to lung cancer 32 (Sluc32) and Susceptibility to colon cancer 4 (Scc4) on chromosome 17 (78 Mb) and Sluc41 and Scc5 on chromosome 18 (20–57 Mb). This evidence concerns the gene MAU2 and malignant colon neoplasm.