Significant linkage with colon tumor development was observed at this same chromosomal location; in Chromosome 17, the region near 74 Mb harbors the Alk gene (anaplastic lymphoma kinase) that has been targeted for the therapy of some types of lung cancer [24] and the Xdh (xanthine dehydrogenase) gene. The gene discussed is ALK; the disease is colonic neoplasm.