Third, we found that several autoantibodies, including ACE2, CSF2, LYZ, MDA5, MOV10, SNRPB, SOX13 and SRP19 significantly associated with higher overall symptom timing score, which may indicate that synthesis of these AABs is triggered at the beginning of the infections and correlated to symptoms that were reported closer to the blood draw. The gene discussed is IFIH1; the disease is infection.