However, for the RSF after imputation (Fig 6), the top 20 genes/ covariates strongly related to CRC identified using RSF with log-rank split-rule are age, stages, molecular subtype, PIPOX, ADPRM, CLCN2, RPS27L, IER5, POLR3B, SLC6A4, KRAS, SGMS2, DUSP4, SLC28A3, SLC9A8, ACOT8, SYTL1, CABLES2, SCAND1, and MAP7D2. The gene discussed is POLR3B; the disease is colorectal carcinoma.