HPDL and colorectal carcinoma: Detecting the expression of 19 genes in 7 CRC cell lines and CCD841CON revealed that HPDL, LGR5, ASCL2, KCNE3, HNF4G, KRT8, KRT18, SLC12A2 and FERMT1 were significantly overexpressed in CRC cell lines (Figure 3B).