ATG16L1 and gastric cancer: Because it is the ATG16L1 rs2241880 G allele that has been previously associated with GC,12 as also evidenced in our current Australian Caucasian cohort, we further subdivided patients into those whose gastric premalignant lesions were more severe (defined as an OLGIM stage III or IV) and those with mild premalignant lesions (OLGIM I or II).