have been associated with IBD,18 enrichment of Prevotella has recently been implicated in gut inflammation,19 and Rhabdochlamydia has been detected in preterm infants and associated with more severe respiratory disease, need for mechanical ventilation and greater mortality.20 Collectively, loss of ZnT2 function is associated with physiologically deleterious changes in the gut microbiome, which may ultimately affect susceptibility to infection, mucosal inflammation, and disease. This evidence concerns the gene SLC30A2 and respiratory system disorder.