PPP4R2 and cancer: Our future research will therefore also focus on elucidating the splicing‐related mechanisms through which DHX38/PRP16 may play a role in the induction of apoptosis upon knockdown in OCCC.DHX38/PRP16 has also been found to have roles outside of the spliceosome; for example, it binds to the protein phosphatase 4 (PP4) protein phosphatase complex, inhibiting the dephosphorylating activity of its PP4C/PP4R2 subunits in both cancer and normal cell lines [40].