Thus, patients with autosomal recessive complete deficiencies in IL-17RA, IL17RC, or ACT1/TRAF3IP2 develop fully penetrant, severe, treatment-refractory mucosal infections by Candida species, termed chronic mucocutaneous candidiasis (CMC) [169–172]. The gene discussed is TRAF3IP2; the disease is chronic mucocutaneous candidiasis.