DNAJB1 and neurodegenerative disease: In neurodegenerative diseases like PD, ER stress has been shown to deregulate redox homeostasis, promoting a dramatic increase in protein deposition due to increase of misfolded proteins aggregation.[62] In fact, glutathione redox homeostasis seems to be essential to proteostasis maintenance through autophagy regulation.[62] mRNA levels of BECN1 did not change consistently with metabolite pretreatment and MPP+ and we observed a beneficial effect from both cat‐sulf and pyr‐sulf via upregulation of Hsp40 expression.