AKT1 and cancer: Also, MYC, one of the proteins associated to cell cycle, seems to be involved in central signaling pathways like MAPK and PI3K‐Akt and it is described as increased in degenerating neurons, supporting the hypothesis that neurodegeneration is related with an inappropriate cell cycle control, similarly to cellular proliferation in cancer.[39] TP53, common to both LMWPM, has already been described as involved in protective mechanisms associated to (poly)phenols,[40, 41] but it is not clear how this can affect downstream metabolism.