Currently, seven forms of HAEs can be distinguished in the nC1‐INH‐HAE group: hereditary angioedema with angiopoietin 1 gene mutation (ANGPT1‐HAE); hereditary angioedema with factor XII gene mutation (FXII‐HAE); hereditary angioedema with kininogen 1 gene mutation (KNG1‐HAE), hereditary angioedema with plasminogen gene mutation (PLG‐HAE), hereditary angioedema with myoferlin gene mutation (MYOF‐HAE), hereditary angioedema with heparan sulfate‐glucosamine 3‐O‐sulfotransferase 6 mutation (HS3ST6‐HAE), and hereditary angioedema of unknown origin (U‐HAE).9, 10, 11, 12, 13, 14. This evidence concerns the gene PLG and hereditary angioedema.