While those higher in COPD included growth factor signaling (VEGFC, FGF7); stress response (STIP1); regulation of cell cycle (RAN, PTPN6); mitochondrial organization (ATP50); kinase signaling (RAC3); and protein localization (GPI) (Figure 1C and D). The gene discussed is PTPN6; the disease is chronic obstructive pulmonary disease.