MCM4 and hepatocellular carcinoma: In addition, the protein level of MCM4 was significantly higher in HCC tissues (high, >75%, location: nuclear, patient ID 983) compared with normal tissues (weak, <25%, location: nuclear, patient ID 1846) based on Human Protein Atlas (HPA) [13] (Figure 2(e)) and western blot validation from 4 pairs of tissues of HCC patients (Figures 2(g) and 2(h), p = 0.0365).