Long et al. identified 14 core genes (PKMYT1, TTK, CHEK1, CDC20, PTTG1, MCM2, CDC25C, MCM4, CCNB1, CDC45, MAD2L1, CCNB2, BUB1, and CCNA2) that are important for lung adenocarcinoma (LUAD) by bioinformatics analysis and may be potential therapeutic targets [22]. This evidence concerns the gene BUB1 and lung adenocarcinoma.