GPT and Encephalopathy: Hepatotoxicity due to ATT was defined as (1) at least a fivefold elevation in alanine transaminase (ALT) and/or aspartate transaminase above the upper limit of normal (2) more than 1.5 mg/dL increase in the total bilirubin level (3) clinical features of acute liver derangement such as loss of appetite, jaundice, vomiting, nausea, encephalopathy and at least a threefold rise in ALT and/or AST levels [3].