Serum CXCL1 concentrations in SLE patients were significantly correlated with the SLEDAI score and RAI of HA IgG ANAs (r = 0.582, p < 0.001; r = 0.552, p < 0.001; respectively) (Fig. 3a, b). Here, CXCL1 is linked to systemic lupus erythematosus.