Among the 10 pro-inflammatory cytokines assessed (Figure 6), concentrations of IL4 and IL12 (Figure 6d,h) were significantly increased (p < 0.05; n = 6), whereas that of IL6 (Figure 6e) significantly decreased in the bro-ALI at 24 h post S1 protein exposure, compared to sham. The gene discussed is IL6; the disease is acute respiratory distress syndrome.