CSF1R and keratitis: In a study utilizing the mouse model of adenovirus keratitis [84], macrophage Fas-Induced apoptosis (MaFIA) transgenic mice, in which the mouse colony stimulating factor 1 receptor promoter (Csf1r) was used to drive expression of a mutant human FK506 binding protein 1A in macrophages and dendritic cells to induce apoptosis, clinical keratitis was reduced and the recruitment of leukocytes was diminished as compared to controls [85].