The hypothesis about the beneficial impact of curcumin supplementation on women with PCOS is because curcumin may support the improvement in complications of PCOS by regulating gene expression—that is, by increasing the gene expression of superoxide dismutase (SOD) and glutathione peroxidase enzymes (GPx)—and cellular signaling [15]. This evidence concerns the gene SOD1 and polycystic ovary syndrome.