INS and polycystic ovary syndrome: Other researchers who have looked at the effects of curcumin on glycemic status, lipid profile, and high-sensitivity C-reactive protein (hs-CRP) levels in overweight/obese women with PCOS found that serum insulin, QUICKI (p < 0.05), and HOMA-IR (p = 0.067) were significantly improved in the group treated with curcumin.