INS and polycystic ovary syndrome: Heshmati et al. [28] reported not only reduced glucose and insulin plasma levels, but also significantly reduced serum dehydroepiandrosterone (DHEA) levels (−26.53 μg/dL; p = 0.035) in patients with PCOS who took curcumin supplements for 12 weeks in doses of 1500 mg per day in comparison to the placebo patients.