Recent meta-analyses and systematic reviews support the health benefits of probiotics in relation to the modulatory effect on the immune system, as reported in the study by Miller et al. [11] showing positive results in cellular immune function responsible for first-line defense against pathogenic microorganisms, or the work by Hajavi et al. [12], in which probiotics could increase systemic interferon (IFN), interleukin 10 (IL-10), and interleukin 12 (IL-12) production, elevate pro-Th1 cytokine immune responses, and decrease the profile of elevated Th2 cytokines in allergic diseases. The gene discussed is IL10; the disease is allergic disease.