On the other hand, in our study, we observed that the levels of apo E and MDA-LDL—MDA-LDL is a major atherogenic factor—were markedly decreased in the ASTX group compared to the control group, suggesting that ASTX may have beneficial effects on the prevention of atherosclerosis in patients with prediabetes and diabetes, whereas TC, TG, LDL-C and HDL-C were not significantly changed. Here, APOE is linked to diabetes mellitus.