BDNF and myeloid sarcoma: Therefore, the aim of this study was to investigate the effect of a lactate threshold training program, designed to improve the quality of life in subjects with MS, by monitoring motor parameters: strength, balance and eye–hand reaction; psychological parameters: self-efficacy and motivation in exercise; blood chemistry parameters: baseline lactate (investigating the possibility of reusing the lactate itself as an energy substrate), BDNF concentrations and DHEAS levels (considered a putative marker of fatigue in MS); and nutrition habits.