As shown in Table 3, significant interactions between CDKAL1-rs7754840 and VDR-rs10783219 on the risk of GDM and GDM subtype 2 (Pinteraction: 0.0121 and 0.0432) as well as interactions between CDKAL1-rs7754840 and MTNR1B-rs10830962 on the risk of GDM and GDM subtype 1 (Pinteraction: 0.0082 and 0.0071) were found. The gene discussed is VDR; the disease is gestational diabetes.