Based on model breast cancer and malignant glioma cell lines, it has been proven that statins reducing the invasiveness of pathological cells act through changes in the level of protein phosphorylation and the activation of protein kinases in Rho/Rho kinase (ROCK) and Rho/Focal adhesion kinase (FAK)/Protein kinase B (Akt) pathways. The gene discussed is AKT1; the disease is malignant glioma.