In observational studies conducted during the COVID-19 outbreak in France, mCD169 expression, as well as the median fluorescence intensity of CD169 between monocytes and lymphocytes (CD169 RMFI), were also associated with the SARS-CoV-2 infection in patients at hospital admission, underlining its importance as an early infection biomarker [13,14,15,16]. Here, SIGLEC1 is linked to infection.