Overexpression of MMP9, MUC4, and HBD2 was observed at 24 h following the treatment with 100 μL sodium hyaluronate 0.15% (SH) of dry eye condition in comparison with the control corneal tissue (p < 0.001; Student’s t-test) (Figure 3e–g). This evidence concerns the gene MUC4 and Keratoconjunctivitis sicca.