qRT–PCR revealed increased inflammatory IL-1β, IL-6, IL-8 expression at 24 h following the induction of dry-eye and 24 h treatment with 100 μL sodium hyaluronate 0.15% (SH) in comparison with the control corneal tissue (p < 0.001; Student’s t-test) (Figure 3b–d). Here, IL1B is linked to Keratoconjunctivitis sicca.