Table 1 lists the medications that epilepsy patients have been taking. These have not been reported to reduce MDR1 protein expression. While the different age range of the epilepsy and control groups may have an effect, the expression of MDR1 was lower in the epilepsy group when compared between control 1 and epilepsy patients of the same age (donors 3, 4 and 6). In young adulthood, the expression of MDR1 in the BBB is highly variable in mice, but not in primates [47,48]. The gene discussed is ABCB1; the disease is epilepsy.