According to several research studies, curcumin hinders the proliferation of cancer cells by the following mechanisms: (i) downregulation of the NF-B/STAT3 signaling pathway [44], (ii) inhibition of different regulatory protein kinases [45], (iii) regulation of apoptosis and other cancer-related pathways [46], (iv) promoting cell cycle arrest [47], (v) suppression of metastasis factors and (vi) promoting ROS-mediated cancer cell death. This evidence concerns the gene STAT3 and cancer.