This is perhaps the main reason why traditional healers combine and/or alternate different plants in their preparations against diabetes, because they can combine in the same preparation the extracts of plants which (1) stimulate the pancreas to release more insulin (secretagogues), (2) help the body use insulin (sensitizers), and (3) block the breakdown of starches and sugars (α-amylase and α-glucosidase inhibitors) such as LP. The gene discussed is INS; the disease is diabetes mellitus.