This was surprising since previous reports from studies performed in astrocytoma, breast cancer, colon cancer and lung cancer, showed that StarD13 depletion inhibited cancer cell migration due to the dysregulation of RhoA activation (Al Haddad et al., 2020; Hanna et al., 2014a; Khalil et al., 2014; Nasrallah et al., 2014). This evidence concerns the gene STARD13 and malignant colon neoplasm.