We found genes involved in bone morphogenesis (CRTAP and WNT9A), inflammation and neuroinflammation (POLR3E, AIM2 and IFNGR1), metabolic disease and obesity (AIM2, DNAH7, CADM2), and cognitive function (CRTAP and CCDC14) from meta‐analysis of distal sensitization and neuropathic‐like pain traits in the two cohorts. This evidence concerns the gene CADM2 and obesity due to melanocortin 4 receptor deficiency.