We also identified genes involved in obesity and adiposity, AIM2 (Gong et al., 2019), IFNGR1 (Locke et al., 2015), DNAH7 (Söhle et al., 2012) and CADM2 (Graff et al., 2017), as well as type 2 diabetes and cardiovascular disease, DNAH7 (Vujkovic et al., 2020), DDX59 (van der Harst & Verweij, 2018), WDR25 (Perry et al., 2014) and CLDN20 (Heid et al., 2010). The gene discussed is CADM2; the disease is obesity due to melanocortin 4 receptor deficiency.