For example, a study of 52 individuals with age‐related hearing loss and 29 non‐hearing impaired individuals demonstrated that the expression of both pro‐apoptosis Bcl‐2 antagonist killer (BAK1) and apoptosis regulator Bcl‐2 (BCL2) are upregulated in blood samples taken from individuals with hearing loss.[20] Specifically, the BAK1:BCL2 ratio was significantly elevated in the group with age‐related hearing loss in correlation with its degree of severity. This evidence concerns the gene BCL2 and hearing loss disorder.