CD8A and neoplasm: Furthermore, blocking the CXCR4‐CXCL12 axis with CXCR4 and/or CXCL12 neutralizing antibodies did not augment the proliferation and IFN‐γ production of tumor‐specific CD8+ T cells co‐cultured with TCN (Figure S12G, Supporting Information), suggesting that targeting CXCR4/CXCL12 would most likely have no effect on the neutrophil suppressive function.