Consistent with our hypothesis, we stimulated neutrophils with NTCS or TTCS from autologous tumor or non‐tumor tissues, and found that, compared to NTCS‐conditioned neutrophils, TTCS‐conditioned neutrophils significantly upregulated both FasL and PD‐L2 expression (Figure 3F) and were induced to more FasL+PD‐L2+ neutrophil subset (Figure 3G). The gene discussed is FASLG; the disease is neoplasm.