Notably, mutations in FAM20A results in enamel‐renal syndrome (ERS) (Jaureguiberry et al., 2012; Kantaputra et al., 2014; Kantaputra et al., 2014; Wang et al., 2013, 2014), a condition characterized by defective mineralization of dental enamel (amelogenesis imperfecta) and calcification within renal tissues (nephrocalcinosis) (Jaureguiberry et al., 2012; Kantaputra, Bongkochwilawan, et al., 2014; Wang et al., 2013, 2014). The gene discussed is FAM20A; the disease is amelogenesis imperfecta type 1G.