On the contrary, compared to siCTRL cells, biochemical analysis of DDR‐silenced melanoma cells revealed that the concomitant depletion of the two receptors decreased the expression of RelB, NF‐κB2 precursor protein p100, and NF‐κB2 p52 processed form, in SKMEL5 and MM099 cells cultured in MMDR conditions, following exposure to BRAFi alone or in combination with MEKi (Fig 8A and B). This evidence concerns the gene RELB and melanoma.