A mouse model of progressive HF induced by transverse aortic constriction (TAC)/myocardial infarction exhibited upregulated BDH1 along with upregulated genes encoding ketone body transporters (MCT1 and MCT2) and increased 13C-BHB use on the basis of nuclear magnetic resonance studies (66). This evidence concerns the gene BDH1 and myocardial infarction.