Of the 86 CAD patients, 39 had 1-vessel disease, 27 had 2-vessel disease and 20 had 3-vessel disease, the plasma SERPINA3 levels increased progressively with the severity of CAD [1-vessel: 80.5(50.8–131.9) μg/mL; 2-vessel:175.4(59.3–321.4) μg/mL; 3-vessel:405.9(82.0–604.9) μg/mL] (Figure 2C, P for trend < 0.001). Here, SERPINA3 is linked to coronary artery disorder.