Therefore, our study detected the protein expression of TRIB3 and FABP1 in GS, IM-GA, early gastric cancer (EGC) and advanced gastric cancer (AGC) by immunohistochemical staining, aimed to clarify their correlation and roles in gastric carcinogenesis, including their associations with clinicopathological features of GC, and their diagnostic and prognostic values. The gene discussed is TRIB3; the disease is gastric cancer.