In univariable logistic regression, Age, BMI, BDNF, BDNF/Adip ratio, hospitalization days, hypertension and respiratory diseases were significantly associated with ICU admission (all p < 0.05), whilst in-hospital death was significantly associated with age, BDNF, hospitalization days, hypertension and respiratory diseases, and ongoing pharmacological treatment (see Supplementary Table 2). The gene discussed is BDNF; the disease is respiratory system disorder.