When we compared a model containing all the classes with a model containing all the factors, we found that FA is slightly better than LCA in predicting some plasma lipid biomarkers (HDL cholesterol, triacylglycerols, blood glucose, apolipoprotein A1, and high-sensitivity C-reactive protein), while LCA is better than FA in predicting the breast cancer risk. The gene discussed is APOA1; the disease is breast cancer.