SYT1 and diabetes mellitus: In a diabetic rat model, expression level of the synaptic proteins including vesicular glutamate transporter-1, syntaxin-1, and synaptotagmin-1 was decreased in the GCL, but the level of dynein motor proteins increased in the GCL after 8 weeks of diabetes, indicating that axonal transport contributes to early signs of neural dysfunction in the diabetic rat retinas (51).