CD8A and neoplasm: In the experiments using VPA alone, there was no significant effect on tumor reduction (p = 0.73; Supplementary Figures 6A,B), nor on the occurrence of metastatic spread (p = 0.54; Supplementary Figure 6C) and no effect on CD4+ or CD8+ T-cells, Tregs or MSCS (Supplementary Figure 6D).